An International Journal for Oncology Research.  

 


May 2009
Volume 11, Number 5
Cover Illustration:
The cover illustration depicts the results from the paper by Leimgruber et.al., wherein tumor associated macrophages (TAM) were shown to cluster within delimited foci with cytoplasmic protrusions for physical interactions with tumor cells.

TABLE OF CONTENTS

Research Article

Aurora-A expression is independently associated with chromosomal instability in colorectal cancer
Yoshifumi Baba, Katsuhiko Nosho, Kaori Shima, Natsumi Irahara, Shoko Kure, Saori Toyoda, Gregory J Kirkner, Ajay Goel, Charles Fuchs and Shuji Ogino
Abstract   Full Article

In Vivo anti-tumor and anti-metastatic activity of administration of sunitinib in preclinical neuroblastoma mouse model
Libo Zhang, Kristen Smith , Amy L Chong , Diana Stempak, Herman Yeger, Paula Marrano, Paul S Thorner, Meredith S Irwin, David R Kaplan and Sylvain Baruchel
Abstract   Full Article

Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs via XBP-1-mediated activation of Akt
Chen Chen Jiang, Fan Yang, Rick F Thorne, Bi Ke Zhu, Peter Hersey and Xu Dong Zhang
Abstract   Full Article

The plasticity of oncogene addiction: Implications for targeted therapies directed to receptor tyrosine kinases.
Vinochani Pillay, Layal Allaf, Alex L Wilding, jacqui f donoghue, Naomi W Court, Sameer Greenall, Andrew M Scott and Terrance G Johns
Abstract   Full Article

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle
Antoine Leimgruber, Cedric Berger, Virna Cortez-Retamozo, Martin Etzrodt, Andita Newton, Peter Waterman, Jose-Luiz Figueiredo, Rainer Kohler, Natalie Elpek, Thorsten R Mempel, Filip K Swirski, Matthias Nahrendorf, Ralph Weissleder and Mikael J Pittet
Abstract With Video   Full Article

Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation
Eirini Trompouki, Ageliki Tsagaratou, Stylianos K Kosmidis, Pascal Dolle, Jun Qian, Dimitris L Kontoyiannis, Wellington V. Cardoso and George Mosialos
Abstract   Full Article

Pharmacodynamic markers for choline kinase downregulation in breast cancer cells
Sridhar Nimmagadda, Kristine Glunde, Martin G Pomper and Zaver M Bhujwalla
Abstract   Full Article

Galectin-1 pro-angiogenic and pro-migratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression
Marie Le Mercier, Shannon Fortin, Veronique Mathieu, Isabelle Roland, Sabine Spiegl-Krienecker, Benjamin Haibe-Kains, Gianluca Bontempi, Christine Deacestecker, Walter Berger, Florence Lefranc and Robert Kiss
Abstract   Full Article

Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma
Mert M Erkan, Carolin Reiser-Erkan, Christoph W Michalski, Stefanie Deucker, Danguole Sauliunaite, Sylvia Streit, Irene Esposito, Helmut Friess and Jorg Kleeff
Abstract   Full Article

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