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February 2010 Volume 12, Number 2
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Cover Illustration:
The cover represents an artistic depiction of the results presented by Clauss et.al., wherein FISH analysis was used to demonstrate genomic gain at the PI3 locus in ovarian cancer. |
TABLE OF CONTENTS
Research Article |
| A mutant of hepatitis B virus X protein (HBx¦¤127) promotes cell growth via a positive feedback loop involving 5-lipoxygenase and fatty acid synthase |
| Qi Wang, Weiying Zhang, Qiang Liu, Xuan Zhang, Na Lv, Lihong Ye and Xiaodong Zhang |
| Abstract Full Article |
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| GAS6/AXL axis regulates prostate cancer invasion, proliferation, and survival in the bone marrow niche. |
| Yusuke Shiozawa, Elisabeth A. Pedersen, Lalit R. Patel, Anne M. Ziegler, Aaron M. Havens, Younghun Jung, Jingcheng Wang, Stephanie Zalucha, Robert D. Loberg, Kenneth J. Pienta and Russell Taichman |
| Abstract Full Article |
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| c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by
phosphatidylinositol 3-kinase and extracellular signal–regulated kinase 1/2 |
| Maggie K. S. Tang, Hong Y. Zhou, Judy W. P. Yam and Alice S Wong |
| Abstract Full Article |
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| In vivo imaging of xenograft tumors using an epidermal growth factor receptor-specific Affibody molecule labeled with a near-infrared fluorophore |
| Haibiao Gong, Joy Kovar, Garrick Little, Huaxian Chen and D. Michael Olive |
| Abstract Full Article |
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| Translocation of p53 to mitochondria is regulated by its lipid binding property to anionic phospholipids and it participates in cell death control |
| Ching-Hao Li, Yu-Wen Cheng, Po-Ling Liao and Jaw-Jou Kang |
| Abstract Full Article |
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| Overexpression of Elafin in ovarian carcinoma is driven by genomic gains and activation of the NF-κB pathway and is associated with poor overall survival |
| Adam Clauss, Vivian Ng, Joyce Liu, Huiying Piao, Moises Russo, Natalie Vena, Qing Sheng, Michelle S Hirsch, Tomas Bonome, Ursula Matulonis, Azra H Ligon, Michael J Birrer and Ronny Drapkin |
| Abstract Full Article |
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| Constitutive expression of the á4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. |
| Robert B Rebhun, Hua Cheng, Jeffrey E Gershenwald, Dominic Fan, Isaiah J Fidler and Robert R Langley |
| Abstract Full Article |
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| Three-dimensional (3D) nuclear telomere architecture is associated with differential time to progression and overall survival in glioblastoma patients
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| Macoura Gajdi, Fortin David, Tsanaclis Ana-Maria, Garini Yuval, Nir Katzir, Yifat Wienburg, Ju Yan, Ludger Klewes, Thomas Klonisch, Regen Drouin and Sabine Mai |
| Abstract Full Article |
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| Bone morphogenetic protein 7 Is expressed in prostate cancer metastases and its effects on prostate tumor cells depends on cell phenotype and the tumor microenvironment |
| Colm Morrissey, Lisha G Brown, Tiffany E Pitts, Robert L Vessella and Eva Corey |
| Abstract Full Article |
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| Phase I study of combination treatment with PTK 787/ZK 222584 and cetuximab for patients with advanced solid tumors; safety, pharmacokinetics, pharmacodynamics analysis |
| Marlies HG Langenberg, Petronella O Witteveen, Nienke AG Lankheet, Jeanine ML Roodhart, Hilde Rosing, Ingeborg JGM van den Heuvel, Jos H Beijnen and Emile E Voest |
| Abstract Full Article |
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